Gross morphological brain changes with chronic, heavy cannabis use
نویسندگان
چکیده
منابع مشابه
Gross morphological brain changes with chronic, heavy cannabis use.
We investigated the morphology of multiple brain regions in a rare sample of 15 very heavy cannabis users with minimal psychiatric comorbidity or significant exposure to other substances (compared with 15 age- and IQ-matched non-cannabis-using controls) using manual techniques. Heavy cannabis users demonstrated smaller hippocampus and amygdala volumes, but no alterations of the orbitofrontal an...
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CONTEXT Cannabis is the most widely used illicit drug in the developed world. Despite this, there is a paucity of research examining its long-term effect on the human brain. OBJECTIVE To determine whether long-term heavy cannabis use is associated with gross anatomical abnormalities in 2 cannabinoid receptor-rich regions of the brain, the hippocampus and the amygdala. DESIGN Cross-sectional...
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AIMS Repeated drug exposure can lead to an approach-bias, i.e. the relatively automatically triggered tendencies to approach rather that avoid drug-related stimuli. Our main aim was to study this approach-bias in heavy cannabis users with the newly developed cannabis Approach Avoidance Task (cannabis-AAT) and to investigate the predictive relationship between an approach-bias for cannabis-relat...
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ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 2015
ISSN: 0007-1250,1472-1465
DOI: 10.1192/bjp.bp.114.151407